Leptin might be a regulator of serum uric acid concentrations in humans

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BEDIR A., Topbas M., TANYERI F., ALVUR M., ARIK N.

JAPANESE HEART JOURNAL, vol.44, no.4, pp.527-536, 2003 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 4
  • Publication Date: 2003
  • Doi Number: 10.1536/jhj.44.527
  • Journal Name: JAPANESE HEART JOURNAL
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.527-536
  • Keywords: leptin, uric acid, obesity, insulin, BODY-MASS INDEX, OBESE GENE, CARDIOVASCULAR RISK, ADIPOSE-TISSUE, WEIGHT, HYPERTENSION, ASSOCIATION, INSULIN, FAT, ATHEROSCLEROSIS

Abstract

Increased serum urate concentration is a frequent finding in patients with hypertension. Since hyperuricemia is associated with obesity, renal disease. hyperlipidemia, and atherosclerosis. whether or not serum urate is a cardiovascular risk factor per se has remained elusive.