The effect of combined treatment of alpha-tocopherol, ascorbic acid, and pyridoxine with NMDA blocker memantine on penicillin-induced epileptiform activity in rats


Aydin D., Yildirim M. , Ayyildiz M., Agar E.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.43, ss.245-250, 2013 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 43 Konu: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.3906/sag-1204-7
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Sayfa Sayıları: ss.245-250

Özet

Aim: To evaluate the effects of coadministration of vitamins alpha-tocopherol, ascorbic acid, and pyridoxine with memantine on a penicillin-induced experimental epilepsy model in rats so as to clarify the eventual interaction between these vitamins and the N-methyl-D-aspartate (NMDA) system.