The effect of combined treatment of alpha-tocopherol, ascorbic acid, and pyridoxine with NMDA blocker memantine on penicillin-induced epileptiform activity in rats

Aydin, Duygu; Yildirim, MEHMET; Ayyildiz, Mustafa; Agar, Erdal

doi:10.3906/sag-1204-7

The effect of combined treatment of alpha-tocopherol, ascorbic acid, and pyridoxine with NMDA blocker memantine on penicillin-induced epileptiform activity in rats

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Aydin D., Yildirim M. , Ayyildiz M., Agar E.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.43, no.2, pp.245-250, 2013 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 43 Issue: 2
Publication Date: 2013
Doi Number: 10.3906/sag-1204-7
Title of Journal : TURKISH JOURNAL OF MEDICAL SCIENCES
Page Numbers: pp.245-250

Abstract

Aim: To evaluate the effects of coadministration of vitamins alpha-tocopherol, ascorbic acid, and pyridoxine with memantine on a penicillin-induced experimental epilepsy model in rats so as to clarify the eventual interaction between these vitamins and the N-methyl-D-aspartate (NMDA) system.