Reduced cerebrospinal fluid levels of interleukin-10 in children with febrile seizures

ŞAHİN, SEVİM; Uysal, Serap; Yentur, Sibel; Kacar, Alper

doi:10.1016/j.seizure.2019.01.008

Reduced cerebrospinal fluid levels of interleukin-10 in children with febrile seizures

ŞAHİN S., Uysal S., Yentur S. P., Kacar A.

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, cilt.65, ss.94-97, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 65
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.seizure.2019.01.008
Dergi Adı: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.94-97
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Purpose: The exact etiology of febrile seizures (FS) is still unclear. However, it is thought that cytokine network activation may have a causative role. Therefore, this study aimed to evaluate the levels of interleukin-12 (IL-12) as a proinflammatory cytokine, interleukin-10 (IL-10) as an anti-inflammatory cytokine, and interferon-beta (IFN-beta), a marker of toll-like receptor-3 activation as a host response to viruses. These cytokine levels were analyzed in the cerebrospinal fluid (CSF) of children after a FS.