Reduced cerebrospinal fluid levels of interleukin-10 in children with febrile seizures
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, vol.65, pp.94-97, 2019 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 65
- Publication Date: 2019
- Doi Number: 10.1016/j.seizure.2019.01.008
- Journal Name: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.94-97
- Open Archive Collection: AVESIS Open Access Collection
- Karadeniz Technical University Affiliated: Yes
Abstract
Purpose: The exact etiology of febrile seizures (FS) is still unclear. However, it is thought that cytokine network activation may have a causative role. Therefore, this study aimed to evaluate the levels of interleukin-12 (IL-12) as a proinflammatory cytokine, interleukin-10 (IL-10) as an anti-inflammatory cytokine, and interferon-beta (IFN-beta), a marker of toll-like receptor-3 activation as a host response to viruses. These cytokine levels were analyzed in the cerebrospinal fluid (CSF) of children after a FS.