A comparison of imipenem monotherapy versus cefoperazone/sulbactam plus amikacin combination treatment in febrile neutropenic cancer patients

Dincol D., Arican A., Aydin F., Samur M., Willke A., Akbulut H., ...Daha Fazla

CANCER JOURNAL - FRANCE, cilt.11, sa.2, ss.89-93, 1998 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 2
  • Basım Tarihi: 1998
  • Dergi Adı: CANCER JOURNAL - FRANCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.89-93
  • Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

Background - Empirical antibiotic therapy with a third-generation cephalosporin or a beta-lactam antibiotic which has broad antibacterial spectrum has been standard treatment in cancer patients with neutropenic fever. This prospective randomized trial was carried out to compare the efficacy of monotherapy (imipenem) with combination therapy (cefoperazone/sulbactam plus amikacin) in the empirical treatment of febrile neutropenia,