Microwave-assisted synthesis and antifungal activity of some new 1H-1,2,4-triazole derivatives

Kahveci B., Özil M., Menteşe E., Bekircan O., Buruk K.

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, cilt.44, sa.12, ss.1816-1820, 2008 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 12
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1134/s1070428008120178
  • Dergi Adı: RUSSIAN JOURNAL OF ORGANIC CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1816-1820
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

A number of 3-aryl-4-arylmethylideneamino-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesized by reaction of the corresponding aromatic aldehydes with 4-amino-3-aryl-1H-1,2,4-triazol-5-ones in anhydrous ethanol under microwave irradiation. The newly synthesized 1H-1,2,4-triazole derivatives were tested for antimicrobial activity. They showed no antibacterial activity but slight mycostatic activity against some Candida species.