Primary neuroendocrine tumor of the prostate with bone metastasis Kemik metastazi{dotless} yapmi{dotless}ş prostati{dotless}n primer nöroendokrin tümörü


Sivrikaya A., KARAGÜZEL E., Kazaz I. O., Tok D. S., Mungan S.

Journal of Clinical and Analytical Medicine, vol.5, no.1, pp.67-68, 2014 (Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 5 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.4328/jcam.768
  • Journal Name: Journal of Clinical and Analytical Medicine
  • Journal Indexes: TR DİZİN (ULAKBİM), Scopus
  • Page Numbers: pp.67-68
  • Keywords: Prostat, Noroendokrin, Tumor, Kemik, Metastaz
  • Karadeniz Technical University Affiliated: Yes

Abstract

Primary neuroendocrine tumors of the prostate are very rare and their biologic behaviour is not yet well described. A case of primary, prostatic, neuroendocrine tumor with bone metastasis is described. A 50-year-old man presented with a 6 months history of frequent urination, difficulty in urination and failure to empty the bladder. Transurethral prostate resection was performed and the pathological examination of the prostate tissue revealed a poorly-differentiated neuroendocrine carcinoma. Meanwhile, cervical magnetic resonance imaging that was planned due to the presence of neck pain revealed a mass lesion in the right paravertebral soft tissue and a pathological compression fracture of the C6 vertebral body. The patient underwent an operation in which C6 corpectomy, placement of homogenous bone graft and obtaining a biopsy specimen were performed. The pathological assessment of the biopsy revealed metastasis of a poorly-differentiated neuroendocrine carcinoma confirming the bone metastasis of the primary neuroendocrine tumor of the prostate.