This study investigated the associations among the life satisfaction, metacognitive awareness and perceived self-efficacy. It also investigated whether life satisfaction, metacognitive awareness and perceived self-efficacy vary according to gender. The study was performed with 492 students attending high schools. The Life Satisfaction Scale, Cognitive Awareness Scale, Self-Efficacy Scale and an Individual Data Form were used for data collection. Pearson correlation coefficient results revealed that life satisfaction was significantly positively correlated with metacognitive awareness (r = .36, p < .001) and self-efficacy (r = .28, p < .001). Multiple regression analysis revealed that metacognitive awareness and self-efficacy accounted for 15 % of life satisfaction (F-(2,F-489) = 45.25, p < .001). Metacognitive awareness ( = .29, p < .001) and self-efficacy ( = .16, p < .001) make a significant original contribution to the model. In addition, the results show that adolescents do not vary according to life satisfaction (F = .10, p = .74, eta(2)= .00), metacognitive awareness (F = .01, p = .91, eta(2) = .00) or self-efficacy (F = 2.21, p = .13, eta(2) = .00). The study results show that metacognitive awareness and self-efficacy are significant predictors of life satisfaction in adolescents.