The diagnostic and prognostic significance of soluble urokinase plasminogen activator receptor in Crimean-Congo hemorrhagic fever

YILMAZ, GÜRDAL; MENTEŞE, AHMET; KAYA, SELÇUK; UZUN, Aysegul; KARAHAN, SÜLEYMAN; KOKSAL, Iftihar

doi:10.1016/j.jcv.2010.11.014

The diagnostic and prognostic significance of soluble urokinase plasminogen activator receptor in Crimean-Congo hemorrhagic fever

YILMAZ G., MENTEŞE A., KAYA S., UZUN A., KARAHAN S. C., KOKSAL I.

JOURNAL OF CLINICAL VIROLOGY, cilt.50, sa.3, ss.209-211, 2011 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 50 Sayı: 3
Basım Tarihi: 2011
Doi Numarası: 10.1016/j.jcv.2010.11.014
Dergi Adı: JOURNAL OF CLINICAL VIROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.209-211
Anahtar Kelimeler: Crimean-Congo hemorrhagic fever, CCHF, suPAR, Prognostic significance, LEVEL
Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background: Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal disease caused by a tick-borne virus from the Bunyaviridae family. It has recently been reported that soluble urokinase-type plasminogen activator receptor (suPAR), secreted from endothelial cells and the mononuclear phagocyte system, one of the main targets of the CCHF virus, is a potential biomarker for several bacterial and viral infection diseases.