The diagnostic and prognostic significance of soluble urokinase plasminogen activator receptor in Crimean-Congo hemorrhagic fever

YILMAZ G., MENTEŞE A., KAYA S., UZUN A., KARAHAN S. C., KOKSAL I.

JOURNAL OF CLINICAL VIROLOGY, vol.50, no.3, pp.209-211, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 3
  • Publication Date: 2011
  • Doi Number: 10.1016/j.jcv.2010.11.014
  • Journal Name: JOURNAL OF CLINICAL VIROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.209-211
  • Keywords: Crimean-Congo hemorrhagic fever, CCHF, suPAR, Prognostic significance, LEVEL
  • Karadeniz Technical University Affiliated: Yes

Abstract

Background: Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal disease caused by a tick-borne virus from the Bunyaviridae family. It has recently been reported that soluble urokinase-type plasminogen activator receptor (suPAR), secreted from endothelial cells and the mononuclear phagocyte system, one of the main targets of the CCHF virus, is a potential biomarker for several bacterial and viral infection diseases.