JOURNAL OF SURGICAL RESEARCH, vol.203, no.2, pp.383-389, 2016 (SCI-Expanded)
Article / Article
JOURNAL OF SURGICAL RESEARCH
Science Citation Index Expanded (SCI-EXPANDED), Scopus
NACA, N-acetylcysteine amid, Acute necrotizing pancreatitis, THIOL ANTIOXIDANT, OXIDATIVE STRESS, EPITHELIAL-CELLS, ACINAR-CELLS, PATHOPHYSIOLOGY, MECHANISMS, MEDIATORS, APOPTOSIS, PROTECTS, INJURY
Karadeniz Technical University Affiliated:
Background: Inflammatory explosion and oxidative stress are important mechanisms of injury in acute necrotizing pancreatitis (ANP). This study investigated the effects of N-acetylcysteine amid (NACA), a novel cell-permeant antioxidant with anti-inflammatory activity, on experimental ANP in rats.