N-acetylcysteine amid reduces pancreatic damage in a rat model of acute necrotizing pancreatitis


TÜRKYILMAZ S. , Usta A., ÇEKİÇ A. B. , Alhan E. , Kural B. V. , Ercin C.

JOURNAL OF SURGICAL RESEARCH, vol.203, no.2, pp.383-389, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 203 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.1016/j.jss.2016.03.004
  • Title of Journal : JOURNAL OF SURGICAL RESEARCH
  • Page Numbers: pp.383-389

Abstract

Background: Inflammatory explosion and oxidative stress are important mechanisms of injury in acute necrotizing pancreatitis (ANP). This study investigated the effects of N-acetylcysteine amid (NACA), a novel cell-permeant antioxidant with anti-inflammatory activity, on experimental ANP in rats.