Image fusion is the production of high-resolution images by combining the spatial details of a high-resolution image with the spectral features of a low-resolution one. Reports of various quality metrics to evaluate the spectral and spatial qualities of fused images have been published. However, metrics may lead to misinterpretation due to inherent limitations in their mathematical algorithms. Hence, the use of additional assessment techniques in quality evaluation is reasonable. The purpose of the study was to compare the performances of several advanced fusion algorithms in order to help users in their choice of an appropriate fusion algorithm. Four different datasets were fused using advanced fusion algorithms, namely UNB PanSharp, Hyperspherical Color Space, High-Pass Filtering, Ehlers, Subtractive, Wavelet Single Band, Gram-Schmidt, Flexible Pixel-Based, and Criteria-Based. The spectral and spatial qualities of the fused images were evaluated using various quantitative procedures to ensure comprehensive and reliable comparison. The results showed that the Flexible Pixel-Based and High-Pass Filtering algorithms were very successful with regard to spatial quality, whereas the Flexible Pixel-Based and Criteria-Based algorithms were very successful with regard to spectral quality. The authors conclude that the Flexible Pixel-Based algorithm can be used for applications that require high spectral and spatial quality.