Change of coagulation parameters after double plateletpheresis

YILMAZ M., DİKMEN T., SÖNMEZ M., AKDOGAN E., DURMUS A., OMAY S. B., ...Daha Fazla

TRANSFUSION AND APHERESIS SCIENCE, cilt.37, sa.2, ss.161-163, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 2
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.transci.2007.07.004
  • Dergi Adı: TRANSFUSION AND APHERESIS SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.161-163
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

In the previous studies, some authors reported that automated apheresis leads to a hypercoagulable state. We tried to find out changes in coagulation parameters after double plateletpheresis in this study. Forty-five donors were recruited to the study, and coagulation parameters were assessed before and after double plateletpheresis. After double plateletpheresis, fibrinogen, factor V, factor VIII and factor IX were decreased compared with the values before apheresis. Although serum levels of this coagulation parameters are decreasing, they are still in the normal limits. Therefore, we suggest that double plateletpheresis is a safe procedure for healthy volunteers taking into account these coagulation parameters. (C) 2007 Published by Elsevier Ltd.