ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, vol.63, no.5, pp.548-554, 2008 (SCI-Expanded)
Article / Article
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
Science Citation Index Expanded (SCI-EXPANDED), Scopus
4H-1,2,4-triazoles, 4-amino-4H-1,2,4-triazoles, 4-arylmethyleneamino-4H-1,2,4-triazoles, 4-arylmethylamino-4H-1,2,4-triazoles, antioxidant activity, ANTICONVULSANT ACTIVITY, SCHIFF-BASES, ACID, ANTIFUNGAL, ANTICANCER, 1,2,4-TRIAZOLES, ANTIBACTERIAL
Karadeniz Technical University Affiliated:
A series of new 3-(4-chlorophenyl)-5-(pyridin-4-yl)-4-(arylmethyleneamino)-4H-1,2,4-triazole derivatives 3 were prepared in good yields by treatment of 4-amino-3-(4-chlorophenyl)-5-(pyridine-4-yl)-4H- 1,2,4-triazole (2) with selected aldehydes. Compounds 3 were reduced with NaBH(4) to afford the corresponding 3-(4-chlorophenyl)-5-(pyridin-4-yl)-4-(arylmethylamino)-4H-1,2,4-triazole derivatives 4. Eighteen new compounds were synthesized and characterized by elemental analyses, IR. (1)H NMR and (13)C NMR spectral data. The compounds were screened for their antioxidant and antiradical activities.