The relationship between dermatological findings and serum interleukin 31 and serum uridine diphosphate glucose ceramide glucosyltransferase levels among patients with chronic kidney disease


Güvercin B. , Kaynar R. K. , Arica D. A. , Kural B. , Ulusoy Ş. , Cansız M. , ...Daha Fazla

HIPPOKRATIA, cilt.23, sa.2, ss.75-80, 2019 (SCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Konu: 2
  • Basım Tarihi: 2019
  • Dergi Adı: HIPPOKRATIA
  • Sayfa Sayıları: ss.75-80

Özet

Background: Cutaneous diseases are observed with increasing duration and severity of renal disease in patients with chronic kidney disease (CKD). This study aimed to elucidate dermatological manifestations at different stages of CKD and determine their relationship with interleukin 31 (IL-31), a T-cell cytokine that induces severe pruritus, and uridine diphosphate (UDP)-glucose ceramide glucosyltransferase (UGCG), an enzyme that metabolizes ceramide, which plays an important role in moisturizing epidermis.