The effect of hesperidin and quercetin on oxidative stress, NF-kappa B and SIRT1 levels in a STZ-induced experimental diabetes model

İSKENDER, HATİCE; DOKUMACIOĞLU, EDA; Sen, Tugba; Ince, Imran; KANBAY, YALÇIN; Saral, Sinan

doi:10.1016/j.biopha.2017.03.102

The effect of hesperidin and quercetin on oxidative stress, NF-kappa B and SIRT1 levels in a STZ-induced experimental diabetes model

İSKENDER H., DOKUMACIOĞLU E., Sen T. M., Ince I., KANBAY Y., Saral S.

BIOMEDICINE & PHARMACOTHERAPY, cilt.90, ss.500-508, 2017 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 90
Basım Tarihi: 2017
Doi Numarası: 10.1016/j.biopha.2017.03.102
Dergi Adı: BIOMEDICINE & PHARMACOTHERAPY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.500-508
Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Objective: The aim of this study is to investigate the roles of SIRT1 and NF-kappa B in the pathogenesis of diabetes mellitus in rats with STZ-induced diabetes and determine the effects of hesperidin and quercetin on oxidative stress and on the levels of SIRT1 and NF-kappa B.