The time to and determinants of first fractures in boys with Duchenne muscular dystrophy

Ma J., McMillan H. J., Karaguzel G., Goodin C., Wasson J., Matzinger M. A., ...More

OSTEOPOROSIS INTERNATIONAL, vol.28, no.2, pp.597-608, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.1007/s00198-016-3774-5
  • Journal Name: OSTEOPOROSIS INTERNATIONAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.597-608
  • Keywords: Duchenne muscular dystrophy, First fractures, Glucocorticoids, Osteoporosis, INCIDENT VERTEBRAL FRACTURES, BONE-MINERAL DENSITY, INTRAVENOUS BISPHOSPHONATE THERAPY, SEVERE OSTEOGENESIS IMPERFECTA, X-RAY ABSORPTIOMETRY, GLUCOCORTICOID INITIATION, CORTICOSTEROID TREATMENT, PEDIATRIC OSTEOPOROSIS, RHEUMATIC DISORDERS, RISK-FACTORS
  • Karadeniz Technical University Affiliated: Yes

Abstract

Boys with vertebral fractures (VF) identified through routine spine radiographs had milder, less symptomatic, and fewer VF compared to those diagnosed with VF following consultation for back pain. Spontaneous (i.e., medication-unassisted) reshaping of fractured vertebral bodies was absent. Long bone fractures were present even before Duchenne muscular dystrophy (DMD) diagnosis in some boys.