Comparative analysis of LC-HRMS profiling, ATR FT-IR spectroscopy, antioxidant, anti-diabetic, and anti-tyrosinase activities of extracts from Cotoneaster frigidus Wall. Ex Lindl. “Cornubia” fruit

Cakmak U., Tuncay F. O., KOLCUOĞLU Y.

Food Research International, cilt.201, 2025 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 201
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1016/j.foodres.2024.115535
  • Dergi Adı: Food Research International
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Compendex, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database, DIALNET
  • Anahtar Kelimeler: Antioxidant, Cotoneaster frigidus Wall. ex Lindl, Enzyme inhibition, FT-IR, LC-HRMS, Phytochemical
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

The antioxidant, total phenolic, flavonoid, and anthocyanidin properties of extracts prepared from Cotoneaster frigidus Wall. ex Lindl. “Cornubia” fruit were examined. In addition, the phenolic profile was analyzed using LC-HRMS, and the surface morphological features were studied using ATR FT-IR. Additionally, the inhibitory potential of the extracts on tyrosinase and α-glucosidase/α-amylase was tested. The highest antioxidant activity values were found in ethyl acetate and methanol extracts. The methanol extract was found to be rich in TFC, TPC and TPA. In the research conducted to designate the phenolic profile, it was found that the extracts contained high levels of fumaric acid and chlorogenic acid. In studies conducted for enzyme inhibition, it was observed that methanol extract gave better results than the standard inhibitor used in studies conducted for tyrosinase. For α-glucosidase/α-amylase, it was determined that ethyl acetate extract gave results close to standard inhibitors. Considering the information obtained, it has been evaluated that the fruits of this plant, which are mostly grown for ornamental purposes plants, may have different application areas.