Synthesis and Characterization of Some New 3-(4-tert-Butylphenyl)-5-phenyl-4H-1,2,4-triazole Derivatives

Bekircan O.

ASIAN JOURNAL OF CHEMISTRY, vol.21, no.2, pp.1017-1023, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 2
  • Publication Date: 2009
  • Journal Name: ASIAN JOURNAL OF CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1017-1023
  • Karadeniz Technical University Affiliated: Yes

Abstract

A series of new 3-(4-t-butylphenyl)-5-phenyl-4-(arylmethylene-amino)-4H- 1,2,4-triazole derivatives 3 were prepared in good yields by treatment of 4-amino-3-(t-butyl-phenyl)-5-phenyl-4H-1,2,4-triazole 2 with selected aldehydes. Compounds 3 were reduced with NaBH(4) to afford the corresponding 3-(4-t-butylphenyl)-5-phenyl-4-(arylmethyl-amino)-4H- 1,2,4-triazole derivatives 4. Ten new compounds were synthesized and characterized by elemental analysis, (1)H NMR, (13)C NMR, IR and mass spectral data.