Cupric Oxide Nanoparticles Induce Cellular Toxicity in Liver and Intestine Cell Lines

Creative Commons License

Abudayyak M. , Guzel E., Ozhan G.

ADVANCED PHARMACEUTICAL BULLETIN, cilt.10, sa.2, ss.213-220, 2020 (ESCI İndekslerine Giren Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Konu: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.34172/apb.2020.025
  • Sayfa Sayıları: ss.213-220


Purpose: The wide application of cupric oxide nanoparticles (copper (II) oxide, CuO-NPs) in various fields has increased exposure to the kind of active nanomaterials, which can cause negative effects on human and environment health. Although CuO-NPs were reported to be harmful to human, there is still a lack information related to their toxic potentials. In the present study, the toxic potentials of CuO-NPs were evaluated in the liver (HepG2 hepatocarcinoma) and intestine (Caco-2 colorectal adenocarcinoma) cells.