Cupric Oxide Nanoparticles Induce Cellular Toxicity in Liver and Intestine Cell Lines
ADVANCED PHARMACEUTICAL BULLETIN, vol.10, no.2, pp.213-220, 2020 (ESCI, Scopus)
- Publication Type: Article / Article
- Volume: 10 Issue: 2
- Publication Date: 2020
- Doi Number: 10.34172/apb.2020.025
- Journal Name: ADVANCED PHARMACEUTICAL BULLETIN
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals
- Page Numbers: pp.213-220
- Open Archive Collection: AVESIS Open Access Collection
- Karadeniz Technical University Affiliated: Yes
Abstract
Purpose: The wide application of cupric oxide nanoparticles (copper (II) oxide, CuO-NPs) in various fields has increased exposure to the kind of active nanomaterials, which can cause negative effects on human and environment health. Although CuO-NPs were reported to be harmful to human, there is still a lack information related to their toxic potentials. In the present study, the toxic potentials of CuO-NPs were evaluated in the liver (HepG2 hepatocarcinoma) and intestine (Caco-2 colorectal adenocarcinoma) cells.