Role of Fanconi anemia/BRCA pathway genes in hepatocellular carcinoma chemoresistance
HEPATOLOGY RESEARCH, cilt.46, sa.12, ss.1264-1274, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 46 Sayı: 12
- Basım Tarihi: 2016
- Doi Numarası: 10.1111/hepr.12675
- Dergi Adı: HEPATOLOGY RESEARCH
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1264-1274
- Anahtar Kelimeler: BRCA1, chemosensitization, DSB DNA repair, Fanconi anemia, hepatocellular cancer, interstrand cross-linker drugs, MESENCHYMAL TRANSITION, MITOMYCIN-C, DNA-REPAIR, CELL-LINES, RESISTANCE, CANCER, EXPRESSION, BRCA1, SENSITIVITY
- Karadeniz Teknik Üniversitesi Adresli: Hayır
Özet
Aim: To investigate the expression of DNA repair genes and the impact of the breast cancer 1, early onset (BRCA1) protein on chemoresistance of hepatocellular carcinoma (HCC).