Role of Fanconi anemia/BRCA pathway genes in hepatocellular carcinoma chemoresistance

FERROUDJ S., Yildiz G., BOURAS M., Iscan E., Ekin U., ÖZTÜRK M.

HEPATOLOGY RESEARCH, cilt.46, sa.12, ss.1264-1274, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 12
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1111/hepr.12675
  • Dergi Adı: HEPATOLOGY RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1264-1274
  • Anahtar Kelimeler: BRCA1, chemosensitization, DSB DNA repair, Fanconi anemia, hepatocellular cancer, interstrand cross-linker drugs, MESENCHYMAL TRANSITION, MITOMYCIN-C, DNA-REPAIR, CELL-LINES, RESISTANCE, CANCER, EXPRESSION, BRCA1, SENSITIVITY
  • Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

Aim: To investigate the expression of DNA repair genes and the impact of the breast cancer 1, early onset (BRCA1) protein on chemoresistance of hepatocellular carcinoma (HCC).