Effects of alpha-lipoic acid on retinal ganglion cells, retinal thicknesses, and VEGF production in an experimental model of diabetes


Kan E., Alıcı O., Kan E. K. , AYAR A.

INTERNATIONAL OPHTHALMOLOGY, vol.37, no.6, pp.1269-1278, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 6
  • Publication Date: 2017
  • Doi Number: 10.1007/s10792-016-0396-z
  • Title of Journal : INTERNATIONAL OPHTHALMOLOGY
  • Page Numbers: pp.1269-1278
  • Keywords: Diabetic retinopathy, Alpha-lipoic acid, Neurodegeneration, Antioxidants, Vascular endothelial growth factor, ENDOTHELIAL GROWTH-FACTOR, FACTOR EXPRESSION, OXIDATIVE STRESS, RETINOPATHY, DEATH, ANTIOXIDANTS, ABNORMALITIES, PROGRESSION, METABOLISM, INHIBITOR

Abstract

The purpose of the present study was to investigate the effect of alpha-lipoic acid (ALA) on the thicknesses of various retinal layers and on the numbers of retinal ganglion cells and vascular endothelial growth factor levels in experimental diabetic mouse retinas.