Effects of alpha-lipoic acid on retinal ganglion cells, retinal thicknesses, and VEGF production in an experimental model of diabetes


Kan E., Alıcı O., Kan E. K., AYAR A.

INTERNATIONAL OPHTHALMOLOGY, cilt.37, sa.6, ss.1269-1278, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 6
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1007/s10792-016-0396-z
  • Dergi Adı: INTERNATIONAL OPHTHALMOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1269-1278
  • Anahtar Kelimeler: Diabetic retinopathy, Alpha-lipoic acid, Neurodegeneration, Antioxidants, Vascular endothelial growth factor, ENDOTHELIAL GROWTH-FACTOR, FACTOR EXPRESSION, OXIDATIVE STRESS, RETINOPATHY, DEATH, ANTIOXIDANTS, ABNORMALITIES, PROGRESSION, METABOLISM, INHIBITOR
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

The purpose of the present study was to investigate the effect of alpha-lipoic acid (ALA) on the thicknesses of various retinal layers and on the numbers of retinal ganglion cells and vascular endothelial growth factor levels in experimental diabetic mouse retinas.