Effects of alpha-lipoic acid on retinal ganglion cells, retinal thicknesses, and VEGF production in an experimental model of diabetes

Kan E., Alıcı O., Kan E. K., AYAR A.

INTERNATIONAL OPHTHALMOLOGY, vol.37, no.6, pp.1269-1278, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 6
  • Publication Date: 2017
  • Doi Number: 10.1007/s10792-016-0396-z
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1269-1278
  • Keywords: Diabetic retinopathy, Alpha-lipoic acid, Neurodegeneration, Antioxidants, Vascular endothelial growth factor, ENDOTHELIAL GROWTH-FACTOR, FACTOR EXPRESSION, OXIDATIVE STRESS, RETINOPATHY, DEATH, ANTIOXIDANTS, ABNORMALITIES, PROGRESSION, METABOLISM, INHIBITOR
  • Karadeniz Technical University Affiliated: Yes


The purpose of the present study was to investigate the effect of alpha-lipoic acid (ALA) on the thicknesses of various retinal layers and on the numbers of retinal ganglion cells and vascular endothelial growth factor levels in experimental diabetic mouse retinas.