Synthesis and antioxidant activities of some 4-benzylidenamino-4,5-dihydro-1<i>H</i>-1,2,4-triazol-5-one derivatives

YUKSEK H., KOLAYLI S., KUCUK M., YUKSEK M., Ocak U., SAHINBAS E., ...Daha Fazla

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, sa.3, ss.715-718, 2006 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2006
  • Dergi Adı: INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
  • Sayfa Sayıları: ss.715-718
  • Anahtar Kelimeler: antioxidant activities, 1,2,4-triazol-5-ones, pK(a) values, 4,5-DIHYDRO-1H-1,2,4-TRIAZOL-5-ONE DERIVATIVES, TITRATIONS
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Eight 3-alkyl(aryl)-4-(3,4-dihydroxybenzylidenamino)-4,5-dihydro-1/./-1,2,4-triazol-5-ones 2 having 4,5-dihydro-1/./-1,2,4-triazol-5-one ring are synthesized by the reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1/./-1,2,4-triazol-5-ones I with 3,4-dihydroxy-benzaldehyde and their antioxidant activities are investigated. In addition, compounds 2b, 2f and 2h are titrated potentiometrically with tetrabutylammonium hydroxide in non-aqueous solvents and the half neutralization potential values and the corresponding pK(a) values are determined. The structures of new compounds are established from spectral data.