Novel Azole-Functionalited Flouroquinolone Hybrids: Design, Conventional and Microwave Irradiated Synthesis, Evaluation as Antibacterial and Antioxidant Agents


MENTEŞE M., DEMİRBAŞ N. , MERMER A., Demirci S., DEMİRBAŞ A. , AYAZ F. A.

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.15, ss.46-64, 2018 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 15 Konu: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.2174/1570180814666170823163540
  • Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
  • Sayfa Sayıları: ss.46-64

Özet

Background: The synthesis of new hybrid molecules consisting of several heterocyclic pharmacophores namely fluoroquinolone, 1,2,4-triazole, 1,3,4-oxadiazole and piperazine was carried out by conventional and successfully optimized microwave mediated techniques.