Novel Azole-Functionalited Flouroquinolone Hybrids: Design, Conventional and Microwave Irradiated Synthesis, Evaluation as Antibacterial and Antioxidant Agents


MENTEŞE M., DEMİRBAŞ N. , MERMER A., Demirci S., DEMİRBAŞ A. , AYAZ F. A.

LETTERS IN DRUG DESIGN & DISCOVERY, vol.15, no.1, pp.46-64, 2018 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.2174/1570180814666170823163540
  • Title of Journal : LETTERS IN DRUG DESIGN & DISCOVERY
  • Page Numbers: pp.46-64

Abstract

Background: The synthesis of new hybrid molecules consisting of several heterocyclic pharmacophores namely fluoroquinolone, 1,2,4-triazole, 1,3,4-oxadiazole and piperazine was carried out by conventional and successfully optimized microwave mediated techniques.