Fetal US and MRI in detection of craniospinal anomalies with postnatal correlation: single-center experience

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Eyüboğlu İ., Dinç G.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.51, sa.3, ss.1211-1219, 2021 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 3
  • Basım Tarihi: 2021
  • Doi Numarası: 10.3906/sag-2011-122
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.1211-1219
  • Anahtar Kelimeler: Fetal MRI, fetal ultrasound, craniospinal malformations, prenatal diagnosis, CENTRAL-NERVOUS-SYSTEM, ULTRASOUND, AGENESIS, DIAGNOSIS
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background/aim: To reveal the contribution of magnetic resonance imaging (MRI) to ultrasound (US) in prenatal diagnosis of fetal craniospinal anomalies by retrospectively comparing the prenatal and postnatal findings. Materials and methods: After institutional review board approval, between January 2010 and May 2020, 301 pregnant women, which had a gestational age between 19-37 weeks (mean 26.5 +/- 6.1 weeks), diagnosed with cranial and spinal anomalies on fetal US and later on imaged with MRI were evaluated, and in 179 of those cases prenatal imaging findings were compared with postnatal findings. Results: A total of 191 fetal craniospinal anomalies were detected in 179 pregnant women. MRI and US diagnosis were completely correct in 145 (75.9%) and 112 (58.6%), respectively. Diagnostic performance of MRI was significantly higher than that of the US (p < 0.05). Both prenatal MRI and US findings were concordant with postnatal diagnosis in 53% of the cases. In 28.7% cases, prenatal MRI contributed to US by either changing the wrong US diagnosis (8.9%), demonstration of additional findings (14%), or confirming the suspicious US diagnosis (5.8%). Conclusion: Due to its high resolution and multiplanar imaging capability, fetal MRI contributes significantly to US in the correct prenatal diagnosis of craniospinal anomalies. This contribution especially is significant in neural tube defects, cortical malformations, and ischemic-hemorrhagic lesions.