Association Between Thoracic CT-Based Automated Vascular Volumetric Analyses and In-Hospital Early Mortality in Acute Pulmonary Embolism: A Pilot Study
22nd INTERNATIONAL MEDICINE AND HEALTH SCIENCES RESEARCHES CONGRESS, Ankara, Türkiye, 18 - 19 Temmuz 2026, ss.253, (Özet Bildiri)
- Yayın Türü: Bildiri / Özet Bildiri
- Basıldığı Şehir: Ankara
- Basıldığı Ülke: Türkiye
- Sayfa Sayıları: ss.253
- Karadeniz Teknik Üniversitesi Adresli: Evet
Özet
Association
Between Thoracic CT-Based Automated Vascular Volumetric Analyses and
In-Hospital Early Mortality in Acute Pulmonary Embolism: A Pilot Study
Objective: To investigate the association
between thoracic computed tomography (CT)-derived automated vascular volumetric
measurements and in-hospital early mortality in patients with acute pulmonary
embolism (PE).
Methods: This retrospective pilot study
included 26 patients with in-hospital early mortality and 26 survivors.
Thoracic CT images were analyzed using the MONAI Auto3DSeg automated
segmentation framework within the 3D Slicer platform. Volumes of the aorta,
brachiocephalic trunk, bilateral subclavian arteries, bilateral brachiocephalic
veins, and superior vena cava were calculated. Demographic characteristics,
comorbidities, laboratory parameters, and Pulmonary Embolism Severity Index
(PESI) scores were also evaluated. Comparisons between groups were performed
using appropriate parametric and non-parametric statistical tests.
Results: The non-survivor group had
significantly higher age (p=0.017), serum creatinine levels (p=0.034), and
total PESI scores (p<0.001). Atrial fibrillation (p=0.034) and
cerebrovascular disease (p=0.011) were also more prevalent among non-survivors.
No statistically significant differences were observed between the groups
regarding the volumetric measurements of the aorta, brachiocephalic trunk,
bilateral subclavian arteries, bilateral brachiocephalic veins, or superior
vena cava (all p>0.05).
Conclusion: Automated thoracic vascular
volumetric measurements were not associated with in-hospital early mortality in
this pilot cohort. In contrast, PESI score, age, serum creatinine level, and
selected comorbidities demonstrated significant associations with mortality.
Larger prospective studies are warranted to determine the prognostic value of
CT-based vascular volumetric measurements in patients with acute pulmonary
embolism.
Keywords: 3D Slicer; Acute pulmonary embolism; MONAI Auto3DSeg; Mortality; Vascular volume