Synthesis and antibacterial activities of some 4,5-dihydro-1H-1,2,4-triazol-5-ones

YUKSEK H., Demirbas A., Ikizler A., JOHANSSON C., CELIK C., Ikizler A.

ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, vol.47, no.4, pp.405-409, 1997 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 47 Issue: 4
  • Publication Date: 1997
  • Journal Name: ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.405-409
  • Karadeniz Technical University Affiliated: Yes

Abstract

Twenty-one new 1-methyl- and 1-ethyl-3,4-disubstituted-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesized and characterised by elemental analysis, H-1-NMR and IR spectra. These new and 16 recently reported derivatives of 4,5-dihydro-1H-1,2,4-triazol-5-one ring were screened for their antibacterial activities.

Twenty-one new 1-methyl- and 1-ethyl-3,4-disubstituted-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesized and characterised by elemental analysis, H-1-NMR and IR spectra. These new and 16 recently reported derivatives of 4,5-dihydro-1H-1,2,4-triazol-5-one ring were screened for their antibacterial activities.