Synthesis and antibacterial activities of some 4,5-dihydro-1H-1,2,4-triazol-5-ones


YUKSEK H., Demirbas A. , Ikizler A., JOHANSSON C., CELIK C. , Ikizler A.

ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, cilt.47, ss.405-409, 1997 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 47 Konu: 4
  • Basım Tarihi: 1997
  • Dergi Adı: ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH
  • Sayfa Sayıları: ss.405-409

Özet

Twenty-one new 1-methyl- and 1-ethyl-3,4-disubstituted-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesized and characterised by elemental analysis, H-1-NMR and IR spectra. These new and 16 recently reported derivatives of 4,5-dihydro-1H-1,2,4-triazol-5-one ring were screened for their antibacterial activities.

Twenty-one new 1-methyl- and 1-ethyl-3,4-disubstituted-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesized and characterised by elemental analysis, H-1-NMR and IR spectra. These new and 16 recently reported derivatives of 4,5-dihydro-1H-1,2,4-triazol-5-one ring were screened for their antibacterial activities.