Electroanalytical Methods for Determination of Calcium Channel Blockers


AĞIN F.

CURRENT ANALYTICAL CHEMISTRY, vol.15, no.3, pp.207-218, 2019 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Review
  • Volume: 15 Issue: 3
  • Publication Date: 2019
  • Doi Number: 10.2174/1573411014666180426165750
  • Journal Name: CURRENT ANALYTICAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.207-218
  • Keywords: Calcium channel blockers, determination, electroanalytical method, validation, heart diseases, therapeutic agents, STRIPPING VOLTAMMETRIC DETERMINATION, SCREEN-PRINTED ELECTRODES, GLASSY-CARBON ELECTRODE, ELECTROCHEMICAL SENSOR, DOSAGE FORMS, PHARMACEUTICAL FORMULATIONS, PASTE ELECTRODE, SERUM SAMPLES, NIFEDIPINE, AMLODIPINE

Abstract

Background: Calcium Channel Blockers (CCBs) are widely used in the treatment of cardiovascular and ischemic heart diseases in recent years. They treat arrhythmias by reducing cardiac cycle contraction and also benefit ischemic heart diseases. Electroanalytical methods are very powerful analytical methods used in the pharmaceutical industry because of the determination of therapeutic agents and/or their metabolites in clinical samples at extremely low concentrations (10-50 ng/ml). The purpose of this review is to gather electroanalytical methods used for the determination of calcium channel blocker drugs in pharmaceutical dosage forms and biological media selected mainly from current articles.