Matrix-induced autologous mesenchymal stem cell implantation versus matrix-induced autologous chondrocyte implantation in the treatment of chondral defects of the knee: a 2-year randomized study

Akgun, Isik; Unlu, Mehmet; Erdal, Ozan; Ogut, Tahir; Erturk, Murat; Ovali, Ercument; Kantarci, Fatih; Caliskan, Gurkan; Akgun, Yamac

doi:10.1007/s00402-014-2136-z

Matrix-induced autologous mesenchymal stem cell implantation versus matrix-induced autologous chondrocyte implantation in the treatment of chondral defects of the knee: a 2-year randomized study

Akgun I., Unlu M. C., Erdal O. A., Ogut T., Erturk M., Ovali E., ...More

ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, vol.135, no.2, pp.251-263, 2015 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 135 Issue: 2
Publication Date: 2015
Doi Number: 10.1007/s00402-014-2136-z
Journal Name: ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.251-263
Karadeniz Technical University Affiliated: Yes

Abstract

Cell-based strategies that combine in vitro- expanded autologous chondrocytes with matrix scaffolds are currently preferred for full-thickness cartilage lesions of the knee a parts per thousand yen2 cm(2). Although this approach is reasonable, continuing advances in the field of cartilage repair will further expand the options available to improve outcomes.