Matrix-induced autologous mesenchymal stem cell implantation versus matrix-induced autologous chondrocyte implantation in the treatment of chondral defects of the knee: a 2-year randomized study


Akgun I., Unlu M. C. , Erdal O. A. , Ogut T., Erturk M., Ovali E., ...More

ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, vol.135, no.2, pp.251-263, 2015 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 135 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.1007/s00402-014-2136-z
  • Journal Name: ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.251-263

Abstract

Cell-based strategies that combine in vitro- expanded autologous chondrocytes with matrix scaffolds are currently preferred for full-thickness cartilage lesions of the knee a parts per thousand yen2 cm(2). Although this approach is reasonable, continuing advances in the field of cartilage repair will further expand the options available to improve outcomes.