Heat transfer occurring in brick, which has an essential place among building filling materials, is a conjugate heat transfer problem consisting of conduction in solid brick walls and natural convection in cavities. Since building filling materials do not have a load-bearing capacity, one of the important features besides easy production and assembly is their high thermal resistance. This high thermal resistance constitutes an essential place in the heat transfer between the building shell and the building parts. High thermal resistance in building bricks is achieved by producing the brick from materials with low thermal conductivity, slowing down the natural convection mechanism in the gaps, or performing both together. This study aims to increase thermal resistance by distributing the gaps at unequal intervals and reducing the horizontal positioning design's natural convection effect with a 45º angle. In the study, a standard brick model was determined for comparison, and the volume/void ratio in different orientations was determined according to the standard element. One standard square hollow brick of 67.5 mm x 95 mm x 95mm, four unequal hollow bricks, one horizontally 45º angled square hollow, and hexagonal hollow brick was in the experimental study produced from PLA filament material on a 3D printer. Temperature analysis at variable thermal powers was performed on the produced models. The relationship between temperature difference and thermal resistance was found for different thermal powers. The results are presented as the variation of the total thermal resistance in the brick with the temperature difference between the brick surfaces. It was seen that the widening gap configuration in the direction of heat transfer is the most suitable configuration for the increase in thermal resistance, and the opposite configuration is the configuration that reduces thermal resistance.