A novel amperometric sensor for ascorbic acid based on poly(Nile blue A) and functionalised multi-walled carbon nanotube modified electrodes

Kul D., Emilia Ghica M., Pauliukaite R., Brett C. M. A.

TALANTA, vol.111, pp.76-84, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 111
  • Publication Date: 2013
  • Doi Number: 10.1016/j.talanta.2013.02.043
  • Journal Name: TALANTA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.76-84
  • Keywords: Poly(Nile blue A), Multi-walled carbon nanotubes, Electropolymerisation, Ascorbic acid determination, Electrochemical impedance spectroscopy, URIC-ACID, ELECTROCATALYTIC OXIDATION, ELECTROCHEMICAL SENSORS, COMPOSITE ELECTRODE, IMPEDANCE SPECTROSCOPY, FILM ELECTRODES, BIOSENSORS, GLUCOSE, POLYMER, REDUCTION
  • Karadeniz Technical University Affiliated: Yes


A new type of modified electrode sensor for ascorbic acid has been prepared by deposition of multi-walled carbon nanotubes (MWCNT) and poly(Nile blue A) on the surface of glassy carbon electrodes. Nile blue A was electropolymerised either beneath (directly on glassy carbon) or onto the MWCNT layer by potential cycling in phosphate buffer solution at pH 6.0. Characterisation of the modified electrodes was carried out by cyclic voltammetry and electrochemical impedance spectroscopy. Quantitative determination of ascorbate was achieved by cyclic voltammetry and fixed potential amperometry in phosphate buffer solution at pH 5.3. The modified electrodes exhibited good sensitivity, wide linear range, a detection limit of 1.6 mu M and good stability, showing that they can be used as sensors for ascorbic acid. There is no interference from compounds commonly found in clinical and pharmaceutical samples and the determination of ascorbic acid in commercial tablet samples was successfully performed. (C) 2013 Elsevier B.V. All rights reserved.