Circulating parameters of oxidative stress and hypoxia in normal pregnancy and HELLP syndrome
ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.27, sa.11, ss.1567-1572, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 27 Sayı: 11
- Basım Tarihi: 2018
- Doi Numarası: 10.17219/acem/74653
- Dergi Adı: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1567-1572
- Anahtar Kelimeler: oxidative stress, carbonic anhydrases, hypoxia, HELLP syndrome, CARBONIC-ANHYDRASE-IX, MARKERS
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Karadeniz Teknik Üniversitesi Adresli: Evet
Özet
Background. The HELLP syndrome (Hemolysis, Elevated Liver enzymes and Low Platelets) is a complication of severe pre-eclampsia, a condition characterized by oxidative stress elevation caused by disequilibrium between lipid peroxidation and antioxidant defense mechanisms, which, in turn, results in endothelial compromise and free radical-mediated cell damage. While several studies have examined the relationship between pre-eclampsia and oxidative stress, research investigating oxidative and hypoxic status in HELLP syndrome is limited.