Circulating parameters of oxidative stress and hypoxia in normal pregnancy and HELLP syndrome

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MENTEŞE A., GÜVEN S., DEMİR S., Sumer A., YAMAN S. O., ALVER A., ...Daha Fazla

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.27, sa.11, ss.1567-1572, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 11
  • Basım Tarihi: 2018
  • Doi Numarası: 10.17219/acem/74653
  • Dergi Adı: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1567-1572
  • Anahtar Kelimeler: oxidative stress, carbonic anhydrases, hypoxia, HELLP syndrome, CARBONIC-ANHYDRASE-IX, MARKERS
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Background. The HELLP syndrome (Hemolysis, Elevated Liver enzymes and Low Platelets) is a complication of severe pre-eclampsia, a condition characterized by oxidative stress elevation caused by disequilibrium between lipid peroxidation and antioxidant defense mechanisms, which, in turn, results in endothelial compromise and free radical-mediated cell damage. While several studies have examined the relationship between pre-eclampsia and oxidative stress, research investigating oxidative and hypoxic status in HELLP syndrome is limited.