Assessment of atherosclerosis risk due to the homocysteine-asymmetric dimethylarginine-nitric oxide cascade in children taking antiepileptic drugs

Emeksiz, Hamdi; SERDAROĞLU, AYŞE; BİBEROĞLU, GÜRSEL; GÜLBAHAR, ÖZLEM; ARHAN, EBRU; CANSU, ALİ; Arga, Mustafa; Hasanoglu, Alev

doi:10.1016/j.seizure.2012.11.007

Assessment of atherosclerosis risk due to the homocysteine-asymmetric dimethylarginine-nitric oxide cascade in children taking antiepileptic drugs

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Emeksiz H. C., SERDAROĞLU A., BİBEROĞLU G., GÜLBAHAR Ö., ARHAN E., CANSU A., ...More

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, vol.22, no.2, pp.124-127, 2013 (SCI-Expanded)

Publication Type: Article / Article
Volume: 22 Issue: 2
Publication Date: 2013
Doi Number: 10.1016/j.seizure.2012.11.007
Journal Name: SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.124-127
Karadeniz Technical University Affiliated: No

Abstract

Purpose: The aim of this study was to assess the atherogenicity risk of antiepileptics in children by investigating the cascade, "hyperhomocysteinemia (HHcy) -> asymmetric dimethylarginine (ADMA) increase -> nitric oxide (NO) decrease", which is thought to contribute to the developmental process of atherosclerosis.