The effects of ascorbic acid on penicillin-induced epileptiform activity in rats


AYYILDIZ M., COSKUN S., Yildirim M. , AGAR E.

EPILEPSIA, cilt.48, ss.1388-1395, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

Purpose: Epileptic seizure results from excessive discharge in a population of hyperexcitable neurons. A number of studies help to document the effects of active oxygen free radical scavengers such as alpha-tocopherol or ascorbic acid (vitamin C). In the present study, we examined the effects of ascorbic acid, at the six different doses, on penicillin-induced epileptiform activity.