Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation


Ucuncu Y., Celik N., Ozturk C., Turkoglu M., Cetin N., KOÇKARA N., ...Daha Fazla

LIFE SCIENCES, cilt.130, ss.31-37, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 130
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.lfs.2015.03.012
  • Dergi Adı: LIFE SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.31-37
  • Anahtar Kelimeler: Glucosamine, IL-1 beta, TNF-alpha, Rat, OXIDATIVE DNA-DAMAGE, HARPAGOPHYTUM-PROCUMBENS, NITRIC-OXIDE, IN-VITRO, ELECTROCHEMICAL DETECTION, CHONDROITIN SULFATE, INDUCED ARTHRITIS, RABBIT MODEL, BROMELAIN, OSTEOARTHRITIS
  • Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

Aims: This study investigates the effect of a new combination of glucosamine hydrochloride, chondroitin sulfate, methylsulfonylmethane, Harpagophytum procumbens root extract (standardized to 3% harpagoside) and bromelain extract (GCMHB) on formalin-induced damage to cartilage tissue in the rat knee joint and evaluates this combination in comparison with another combination of glucosamine hydrochloride, chondroitin sulfate and methylsulfonylmethane (GKM).