Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation

Ucuncu, YILMAZ; Celik, Nuray; Ozturk, Cengiz; Turkoglu, Murat; Cetin, Nihal; KOÇKARA, NİZAMETTİN; Sener, Ebru; Dundar, Cihat; Arslan, Aynur; DOĞAN, Hasan; Kurt, Nezahat; Suleyman, Halis

doi:10.1016/j.lfs.2015.03.012

Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation

Ucuncu Y., Celik N., Ozturk C., Turkoglu M., Cetin N., KOÇKARA N., ...Daha Fazla

LIFE SCIENCES, cilt.130, ss.31-37, 2015 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 130
Basım Tarihi: 2015
Doi Numarası: 10.1016/j.lfs.2015.03.012
Dergi Adı: LIFE SCIENCES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.31-37
Anahtar Kelimeler: Glucosamine, IL-1 beta, TNF-alpha, Rat, OXIDATIVE DNA-DAMAGE, HARPAGOPHYTUM-PROCUMBENS, NITRIC-OXIDE, IN-VITRO, ELECTROCHEMICAL DETECTION, CHONDROITIN SULFATE, INDUCED ARTHRITIS, RABBIT MODEL, BROMELAIN, OSTEOARTHRITIS
Karadeniz Teknik Üniversitesi Adresli: Hayır

Özet

Aims: This study investigates the effect of a new combination of glucosamine hydrochloride, chondroitin sulfate, methylsulfonylmethane, Harpagophytum procumbens root extract (standardized to 3% harpagoside) and bromelain extract (GCMHB) on formalin-induced damage to cartilage tissue in the rat knee joint and evaluates this combination in comparison with another combination of glucosamine hydrochloride, chondroitin sulfate and methylsulfonylmethane (GKM).