Paragangliomas of the head and neck


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Isik A. C. U. , Imamoglu M., Erem C. , Sari A.

MEDICAL PRINCIPLES AND PRACTICE, cilt.16, ss.209-214, 2007 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 16 Konu: 3
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1159/000100392
  • Dergi Adı: MEDICAL PRINCIPLES AND PRACTICE
  • Sayfa Sayıları: ss.209-214

Özet

Objectives: The purpose of this study was to determine the clinical characteristics of carotid body tumors and to analyze the benefits of different treatment modalities. Subjects and Methods: The clinical records of 13 patients with paragangliomas treated during the period of 1995-2005 were reviewed for age at diagnosis, sex, initial symptoms, duration of symptoms, evidence of secretory function, family history, radiographic studies, pre- and posttreatment cranial nerve deficits, multicentric tumors, angiography, operative procedures and findings, and complications. The diagnoses were established by computerized tomography and magnetic resonance imaging scanning. Angiography was performed on 3 patients with carotid body tumor. Results: All of the patients were followed up for a duration ranging from 16 months to 9 years. The median follow-up was 5 years. Of all 18 head and neck tumors confirmed in 13 patients, 16 were in the carotid body, 1 in the vagus nerve and 1 in the middle ear cleft. Four patients had multiple paragangliomas, 2 bilateral synchronous and 1 bilateral asynchronous paragangliomas. The remaining patient had 3 asynchronous paragangliomas, i.e. left jugulotympanic, right carotid body and left vagal paraganglioma. All patients underwent successful surgical resection of the tumor after appropriate preoperative investigation. Conclusion: This study shows that surgical treatment is acceptably safe and effective in treating these neoplasms. Copyright (C) 2007 S. Karger AG, Basel.