A study on ester formylhydrazones
JOURNAL OF HETEROCYCLIC CHEMISTRY, cilt.35, sa.2, ss.377-380, 1998 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 35 Sayı: 2
- Basım Tarihi: 1998
- Doi Numarası: 10.1002/jhet.5570350220
- Dergi Adı: JOURNAL OF HETEROCYCLIC CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.377-380
- Karadeniz Teknik Üniversitesi Adresli: Evet
Özet
A series of ester formylhydrazones 2 were synthesized from the reaction of alkyl imidate hydrochlorides 1 with formylhydrazine. Treatment of 2 with hydrazine hydrate, ethyl carbazate and tert-butyl carbazate led to the formation of 3-alkyl-4-amino-, 3-alkyl-4-ethoxycarbonylamino- and 3-alkyl-4-tert-butoxycarbonylamino-4H-1,2,4-triazoles 3-5, respectively. Reaction of compounds 2 with formylhydrazine gave N,N'-diformylhydrazine 6. Compounds 2 were reacted with 2,5-dimethoxytetrahydrofuran to afford 3-alkyl-4-(1H-pyrrol-1-yl)-4H-1,2,4-triazoles 8.