Serum levels of androgens and prostate-specific antigen in endometriosis

Evsen M. S., Sak M. E., Soydinc H. E., GÜVEN S., Basaranoglu S., Hatipoglu N. K., ...More

CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY, vol.41, no.4, pp.432-435, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 4
  • Publication Date: 2014
  • Doi Number: 10.12891/ceog16712014
  • Journal Name: CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.432-435
  • Keywords: Endometriosis, Androgens, Prostate-specific antigen, POLYCYSTIC-OVARY-SYNDROME, PRIMATE OVARY, IN-VITRO, MARKER, WOMEN, GROWTH, EXCESS
  • Karadeniz Technical University Affiliated: Yes

Abstract

Objective: The aim of the present study was to evaluate the levels of serum androgens and prostate-specific antigen (PSA) levels in patients with endometriosis. Materials and Methods: Patients with Stage III/IV(advanced stage) endometriosis were compared to controls with respect to basal serum levels of total testosterone (T), free testosterone (fT), androstenedion (A), dehydroepiandrosterone (DHEA), dehydroepiandrosterone-sulphate (DHEA-S), and PSA in the early follicular phase of menstrual cycle for this prospective case control study. Results: Level of T, IT, A, DHEA, and DHEA-S were higher in patients with endometriosis when compared to control subjects, but the difference was not statistically significant. The mean PSA level was 0.0074 +/- 0.0120 ng/ml in patients with endometriosis and 0.0059 +/- 0.0056 ng/ml in control group and there was no statistically significant difference between groups (p = 0.58). Conclusion: Serum basal androgens and PSA levels are higher in endometriosis group with respect to control but the differences are not statistically significant.