Wooden buildings with many advantages such as being lightness, durability, earthquake resistant, healthy, insulating, and aesthetic are suitable for all kinds places especially in earthquake zones. The aim of this study is to investigate the effect of some technological properties of the plywood panels manufactured from some wood species grown in Turkey on seismic resistant performance of shear walls. Two different wood species (scots pine, spruce) and two different number of layers (5 and 7) were used in this study. Phenol formaldehyde resin was used as adhesive for plywood panels manufacturing. Bending strength and modulus of elasticity and density of plywood panels manufactured in an industrial plant were determined according to TS EN 310 and TS EN 323, respectively. Plywood panels were tested on full scale shear wall to determine the actual structural performance, maximum load and maximum displacement under the monotonic load according to ASTM E72. As a result of the study, the bending strength and modulus of elasticity values increased with number of layers for scots pine while the values decreased with number of layers for spruce. It was determined that maximum load values were increased for shear wall of each group with increasing bending strength and modulus of elasticity values of the plywood panels, while maximum displacement values of them were decreased.