Granular cell tumor in a child: A rare case report

Yilmaz Z., ERSÖZ Ş.

INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY, vol.63, no.3, pp.478-480, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 63 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.4103/ijpm.ijpm_495_19
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Page Numbers: pp.478-480
  • Keywords: Child, granular cell tumor, subcutaneous nodule
  • Karadeniz Technical University Affiliated: Yes


A granular cell tumor (GCT) is a rare, usually benign soft tissue neoplasm that is commonly seen in the head and neck region. It is derived from the Schwann cells of the peripheral nerves. GCT is uncommon in children. 6-year-old girl was referred to our hospital for swelling over her left scapula, and a surgical excision was performed to remove the mass. Microscopically, the tumor was composed of cells with large granular cytoplasm and small oval to round nuclei. These cells stained positively for the following proteins: S-100, CD68, neuron-specific enolase, calretinin, and inhibin A. A GCT is usually benign, with a good prognosis, and less than 2% of the cases are reported to be malignant. It is worth noting that such tumors may arise in atypical locations and there is a possibility of malignancy.