ANNALS OF NEUROLOGY, cilt.76, sa.6, ss.880-890, 2014 (SCI-Expanded)
ObjectivePrevious studies assessing seasonal variation of relapse onset in multiple sclerosis have had conflicting results. Small relapse numbers, differing diagnostic criteria, and single region studies limit the generalizability of prior results. The aim of this study was to determine whether there is a temporal variation in onset of relapses in both hemispheres and to determine whether seasonal peak relapse probability varies with latitude.