Olfactory neuroblastoma: A case report

Uslu G. H., CANYILMAZ E., Zengin A. Y., AYDIN MUNGAN S., Yoney A., BAHADIR O., ...More

ONCOLOGY LETTERS, vol.10, no.6, pp.3651-3654, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 10 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.3892/ol.2015.3821
  • Journal Name: ONCOLOGY LETTERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.3651-3654
  • Keywords: esthesioneuroblastoma, olfactory neuroblastoma, surgical resection, radiotherapy, ESTHESIONEUROBLASTOMA, RADIOTHERAPY, CHEMOTHERAPY, TUMORS
  • Karadeniz Technical University Affiliated: Yes


Olfactory neuroblastoma (ON) is a rare type of malignant neoplasm originating from the olfactory neuroepithelial cells of the nasal cavity. ON is also known as esthesioneuroblastoma or neuroendocrine carcinoma. The malignancy accounts for <3% of tumors originating in the nasal cavity. Through the nasal cavity, ON may infiltrate the sinuses, the orbit and the cranium. The tumor is characterized by a pattern of slow growth and local recurrences. Treatment options are surgical excision or surgery combined with a radiotherapy (RT) and/or chemotherapy combination treatment. The present study reports the case of a 69-year-old patient with a mass in the nasal cavity who was treated by combined surgical excision and RT. The literature for ON and the treatment of the tumor are also discussed.