THE ACTION OF AMYL NITRITE AND ISOSORBIDE DINITRATE ON THE CONTRACTILITY OF SPHINCTER OF ODDI OF GUINEA-PIGS

GOCER F., YARIS E., TUNCER M.

GENERAL PHARMACOLOGY-THE VASCULAR SYSTEM, vol.25, no.5, pp.995-999, 1994 (SCI-Expanded) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 5
  • Publication Date: 1994
  • Doi Number: 10.1016/0306-3623(94)90109-0
  • Journal Name: GENERAL PHARMACOLOGY-THE VASCULAR SYSTEM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.995-999
  • Keywords: SPHINCTER OF ODDI, AMYL NITRITE, ISOSORBIDE DINITRATE, SODIUM NITROPRUSSIDE, METHYLENE BLUE, N-G-MONOMETHYL-L-ARGININE (L-NMMA), NITRIC OXIDE, ACETYLCHOLINE, SOLUBLE GUANYLATE-CYCLASE, VASCULAR SMOOTH-MUSCLE, CYCLIC-GMP, METHYLENE-BLUE, GLYCERYL TRINITRATE, OXIDE, RELAXATION, NITROPRUSSIDE, ACTIVATION, NITRATES
  • Karadeniz Technical University Affiliated: No

Abstract

1. This study was designed to investigate whether relaxation of isolated guinea-pig sphincter of Oddi preparation by nitrates is mediated by guanylate cyclase activation indirectly by nitric oxide (NO), as in vascular tissues.