A rare localization of a common disease: Primary uterine Non-Hodgkin lymphoma mimicking leiomyosarcoma

Goksel S., Karaman E., Karacin P., ERSÖZ Ş.

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, cilt.18, sa.4, ss.1205-1207, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 4
  • Basım Tarihi: 2022
  • Doi Numarası: 10.4103/jcrt.jcrt_435_22
  • Dergi Adı: JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.1205-1207
  • Anahtar Kelimeler: Extra-nodal lymphoma, FDG PET/CT, post-menopausal bleeding, uterus, EXTRANODAL INVOLVEMENT, PET/CT
  • Karadeniz Teknik Üniversitesi Adresli: Evet

Özet

Genitourinary system lymphomas comprise a small part of extra-nodal lymphomas (ENLs). ENLs of uterine origin are extremely rare and are often confused with gynecological malignancies. We present an 80-year-old female patient diagnosed with diffuse large B-cell lymphoma (DLBCL) with a single focus of the uterus. The patient's only complaint was abnormal uterine bleeding. Magnetic resonance imaging revealed an intramural-subserous-submucous multiple mass lesion with minimal contrast enhancement mimicking leiomyosarcoma. Diffuse pathological 18F-fluorodeoxyglucose uptake was detected in the entire uterus corpus and cervix on positron emission tomography/computed tomography (PET/CT) scanning. The pathology of the endocervical and endometrial curettage material obtained was DLBCL; the patient was diagnosed with ENL, and a single focus was the uterus. ENLs should be considered in the differential diagnosis of gynecological malignancies in patients with abnormal uterine bleeding. PET/CT is crucial in showing metabolically active spread areas in these patients.