Investigations of factors affecting mortality in our ECMO (Extracorporeal membrane oxygenation) applications

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Erkan G., EROĞLU A.



Aim: Extracorporeal membrane oxygenation (ECMO) is a life support application used for life-threatening pulmonary or cardiac injuries that could not be treated with traditional treatment strategies successfully. In our study, we investigated factors affecting mortality in patients using ECMO in our clinic.Material and Methods: In the study, 74 patients over the age of 18 who used ECMO were retrospectively examined. Patients were divided into two groups as those who survived after ECMO support (Group 1) and those who ended up with mortality (Group 2). Demographic data and comorbidities of patients, APACHE-2 score, RESP score, indications, applied ECMO type, inotropic treatments, blood products used and their quantities, non-ECMO support applications, and complications were studied.Results: Of the 74 ECMO patients, 43 (58.11%) were male and 31 (41.89%) were female. The number of patients who ended up with mortality was 42(56.76%) and the number of those who survived was 32 (43.24%). Age, APACHE 2 and RESP scores, and ECMO flow were found to be statistically significantly higher in the group with mortality than the in the survival group (p<0.05). In addition, the rate of thrombocytopenia and the quantity of thrombocyte suspension used were higher in the mortality group. The causes of mortality were cardiac failure in 15 (35.71%) patients, hemorrhage in 7 (16.67%) patients, sepsis in 7 (16.67%) patients, multiple organ dysfunction in 6 (14.29%) patients, renal failure in 5 (11.9%) patients, and neurologic insufficiency in 2 (4.76%) patients. Discussion: The mortality rate could be higher than the survival rate during ECMO applications as in our study. Knowing the causes of mortality is important to take measures.