JOURNAL OF UROLOGY, vol.175, no.6, pp.2350-2353, 2006 (SCI-Expanded)
Article / Article
JOURNAL OF UROLOGY
Science Citation Index Expanded (SCI-EXPANDED), Scopus
muscle contraction, seminal uesicles, testis, sildenafil, rats, Wistar, PREMATURE EJACULATION, NITRIC-OXIDE, VAS-DEFERENS, IN-VITRO, DYSFUNCTION, EFFICACY, TENSION, VIAGRA, DRUGS
Karadeniz Technical University Affiliated:
Purpose: Sildenafil is reported to regulate smooth muscle contractility through nitric oxide-cyclic guanosine monophosphate, not only in the corpus cavernosum. Its possible effects on seminal vesicle contractility might be of importance with respect to premature ejaculation. We investigated the effects of sildenafil citrate (Pfizer, New York, New York) on agonist induced isometric contractions of the rat seminal vesicle in vitro.