Polyneuropathy, Myopathy and Hepatitis in a Child with Nephrotic Syndrome
TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, vol.25, no.3, pp.309-312, 2016 (ESCI, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 25 Issue: 3
- Publication Date: 2016
- Doi Number: 10.5262/tndt.2016.1003.16
- Journal Name: TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.309-312
- Open Archive Collection: AVESIS Open Access Collection
- Karadeniz Technical University Affiliated: Yes
Abstract
Acute sensorimotor polyneuropathy that resembles Guillain-Barre syndrome (GBS) and hepatitis is rarely accompanied with nephrotic syndrome. Its underlying immunological mechanisms are unclear. Involvement of immunological processes against common antigens in the glomerulus, peripheral nervous system and liver has been suggested. We describe a 5-year-old boy patient with acute sensorimotor polyneuropathy, myopathy and hepatitis that was accompanied with nephrotic syndrome. Renal biopsy showed membranoproliferative glomerulonephritis (MPGN). He was in remission on nephrotic syndrome and polyneuropathy at his 6-month follow-up. Approximately 40 cases have been reported in the literature and to our knowledge he is the first patient with these four conditions. In conclusion, this case report suggests that the same underlying immunological mechanisms appear in relation with each other.