Central venous catheters are commonly used devices in pediatric patients who require treatment in intensive care units. In addition to the advantages of a venous access and hemodynamic monitorisation catheters may also cause severe complications. The malposition of the catheter is one of the reasons for these complications. Despite immediate radiologic confirmation of the catheter position, the catheter may migrate spontanously in hours or days or even weeks after the procedure. We wish to submit two cases treated in our pediatric intensive care unit. One of them has a subclavian catheter, which migrates spontanously in days; its position was confirmed by radiological scanning after the procedure. The other one has a femoral catheter, which curled after being placed with difficulty and it became dysfunctional.