The effects of E-cadherin and bcl-2 on prognosis in patients with breast cancer


Kavgaci H. , YILDIZ B., FİDAN E. , REIS A. , ÖZDEMİR F. , ÇOBANOĞLU Ü. , ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.111, no.9, pp.493-497, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 111 Issue: 9
  • Publication Date: 2010
  • Title of Journal : BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Page Numbers: pp.493-497

Abstract

Background: Breast cancer is the most common malignancy in women. Axillary lymph node involvement and tumor size are the most significant prognostic factors in breast cancer. However, more factors are needed for evaluating the prognosis and individualizing the treatment in these patients. Intracellular adhesion molecule E-cadherin, antiapopitotic protein bcl-2, and p53 might have predictive and prognostic properties in breast cancer.