Determination of cerebral edema with serial measurement of optic nerve sheath diameter during treatment in children with diabetic ketoacidosis: a longitudinal study

Kendir O. T., YILMAZ H. L., ÖZKAYA A. K., TURAN İ., Gokay S. S., Bilen S., ...More

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, vol.32, no.9, pp.943-949, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 9
  • Publication Date: 2019
  • Doi Number: 10.1515/jpem-2019-0016
  • Journal Name: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.943-949
  • Keywords: cerebral edema, diabetic ketoacidosis, optic nerve sheath diameter measurement, TRANSORBITAL ULTRASOUND MEASUREMENT, INCREASED INTRACRANIAL-PRESSURE, BEDSIDE SONOGRAPHIC MEASUREMENT, INVASIVELY MEASURED ICP, PEDIATRIC-PATIENTS, ULTRASONOGRAPHY, PREDICTOR, ONSD
  • Karadeniz Technical University Affiliated: Yes

Abstract

Background: Cerebral edema is a fatal complication that can occur in children with diabetic ketoacidosis (DKA). Its clinical signs are generally not explicit, and subclinical cerebral edema can occur. This study is one of the few longitudinal studies conducted to identify cerebral edema in patients with DKA by measuring the optic nerve sheath diameter (ONSD). The aim of this study was to investigate cerebral edema in children with DKA with serial measurement of ONSD, which is an early and reliable indicator of cerebral edema, and to monitor changes in ONSD during therapy.