The effect of low molecular weight heparin on salvaging the zone of stasis in an experimental burn model


URALOĞLU M. , LİVAOĞLU M. , AGDOĞAN Ö., ERSÖZ Ş. , Karacal N.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.48, no.3, pp.653-660, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.3906/sag-1710-73
  • Title of Journal : TURKISH JOURNAL OF MEDICAL SCIENCES
  • Page Numbers: pp.653-660

Abstract

Background/aim: Multiple zones of injuries are formed after burns, consisting of a zone of coagulative necrosis, a zone of hyperemia, and a zone of stasis, in which progressive microcirculatory thrombosis leads to degeneration and deepening of the wound. We used an experimental rat comb burn model to test the hypothesis that use of low molecular weight heparin (LMWH) may save the zone of stasis.