The effect of low molecular weight heparin on salvaging the zone of stasis in an experimental burn model


URALOĞLU M. , LİVAOĞLU M. , AGDOĞAN Ö., ERSÖZ Ş. , Karacal N.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.48, ss.653-660, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 48 Konu: 3
  • Basım Tarihi: 2018
  • Doi Numarası: 10.3906/sag-1710-73
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Sayfa Sayıları: ss.653-660

Özet

Background/aim: Multiple zones of injuries are formed after burns, consisting of a zone of coagulative necrosis, a zone of hyperemia, and a zone of stasis, in which progressive microcirculatory thrombosis leads to degeneration and deepening of the wound. We used an experimental rat comb burn model to test the hypothesis that use of low molecular weight heparin (LMWH) may save the zone of stasis.