© 2020. Turk Hij Den Biyol Derg. All rights reserved.Objective: The objective of the study is to minimize the latest arrival time to assembly areas in a determined region. The novel mathematical model is proposed for this problem handled. In the region, taking into account the four different scenarios that may occur as a result of the earthquake, the most suitable plan for drinking water distribution is created under each scenario. Methods: The problem addressed in the study is analyzed as a vehicle routing problem. Optimization techniques are generally used in solving the vehicle routing problem. Optimization can be expressed as “searching the best” regarding the purpose of the decision maker under certain conditions (constraints). Thus, the phrase “finding the most suitable route” can be used for the vehicle routing problem. In this study, using the mathematical modeling approach, which is one of the optimization techniques, the best route that provides minimizing the latest arrival time to the assembly areas is proposed for decision makers. Results: Within the scope of the study, different damage levels that may occur after the earthquake are examined in the different scenarios for Sakarya, Turkey. The latest arrival times to assembly areas increase as the damage that may occur after the earthquake increases. The arrival times to the assembly areas are also different according to scenarios, because the optimum routes change for these scenarios. Conclusion: In this study, the drinking water distribution problem to assembly area is handled. The proposed mathematical model is run for different scenarios and the latest arrival times for each assembly area are determined. The optimum routes obtained are compared for these scenarios. It has aimed that, the proposed method will be used by organizations’ aims to improve their disaster strategies.